Chemical Composition and Bioactive Potential of Extracts from Diospyros capricornuta F. White against Aspergillus flavus and Aspergillus parasiticus

Diospyros capricornuta is an endemic species widely distributed along the coast of Tanzania that used as food condiments and traditional medicine. The chemical compositions leaves, stem-bark, root-bark extracts; their bioactive potentials against Aspergillus flavus parasiticus were investigated. samples D. extracted using Soxhlet apparatus resultant extracts analyzed Gas Chromatography-Mass Spectrometry (GC-MS). A total 14 compounds identified from extracts, whereby 2,4-di-tert-butylphenol was most abundant compound in all extracts. growth aflatoxin production inhibitions A. determined via antifungal antiaflatoxigenic bioassays at concentrations 0.0, 62.5, 125.0, 250.0 µg/mL a poisoned-food method. High-Performance Liquid Chromatography (HPLC) technique to quantify aflatoxins after evaluate inhibitions. stem-bark highest dose inhibited by for over 99% 94%. Overall, results show are potential inhibitors parasiticus-the producers aflatoxins.
 Keywords: capricornuta; Growth inhibitions; Aflatoxin flavus; parasiticus.